Just Answers - Relationships

Problematic issues in a relationship are often not as clear cut as they seem because both genders view aspects of the relationship differently. Women appear to h

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ave more complaints about their spouses and the state of their marriages, compared to men (Brehm 1985). This could be because women’s expectations of the union h

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ave risen over the years. They are now more critical and want much more, while men are tending to retreat and to give less. In recent years, women have initiated

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the break-up of more dating and marriages than men. Although the underlying causes for break-ups are unknown, there are some common issues which cause the most

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

conflict, affecting the partners in different ways. The main one is unrealistic expectations of partners or situations.

Expectations are transmitted dir

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ectly by what we hear and indirectly by what we see. A new relationship in the same space brings expectations to life and will develop problems when those expec

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tations are unreasonable. Our desire for security and perfection breeds the most unrealistic expectations which we then wait, in vain, to be fulfilled by our par

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tners. Of course, they won't, and the first stirrings of dissatisfaction begins. Conflicts caused by unexpressed and unfulfilled expectations are very common and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

can lead to great disappointment and frustration. It is a good habit to stop for a moment when you’re disappointed, ask yourself what you expected and compare i

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t to what you actually received. The difference in fulfilment and expectation will reveal the gap in perception between the two of you. Noting the degree

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

of discrepancy, which may be unconsciously affecting your relationship, will help you to adjust future expectations. Always try to be reasonable in what you expe

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ct – that way you will sometimes get a pleasant surprise, rather than being unreasonable and disappointed.

Discuss Innermost Feelings
Partners canno

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t read minds so be clear about what you expect, otherwise you’ll both have trouble working as a team. You have to share your perspectives with each other,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

which means being totally honest and discussing innermost feelings, hopes, strengths and weaknesses long before marrying or setting up home. Our partners cannot

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fulfil all our needs and so personal expectations cannot be too selfish or unreal.

In order to have a good relationship, the positives must outweigh the negati

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ves by a large percentage. If negativity is creeping into your relationship it also crowds out the positive. It is like water seeping through walls, eventually w

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

eakening the structure. People usually feel motivated around others who are positive and energising, as well as those who help them to feel good about themselves

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

. However, pushing aside or neglecting to address real problems is not the answer either, and can be just as harmful to the relationship.

So if you find yoursel

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

f increasingly nitpicking, nagging, criticising or withdrawing, you need to stop and really reflect for a while on the effects of those actions, which could be c

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ounter-productive. Instead, strive to communicate effectively, to praise much more and to practise balanced negotiation to get what you hope for or truly desire.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Marketing has changed dramatically during the past decade with the advent of the Internet and Search Engines such as Google and Yahoo. In simpler times, the approach of creating aggressive strategies to propel sales, was very Pavlovian - Stimulus - Response, you placed the ad, generated the demand and the sales happened, not much focus was given to the customer.

Are you an entrepreneur who is opening a dollar store? Then never lose sight of the importance of cost reduction to the success of your business. Cost reduction should take place from the day you start your planning. One of the most important areas for focus is the Cost-Of-Goods-Sold.

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