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Nowadays, the problem of abortion, and, consequently, the problem of antiabortion become vitally important particularly for well-developed, post-industrial societies. It is evident that it

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is not a problem of an individual anymore but a really social problem because it concerns not only the health of a woman but it also produces a serious impact on a demographic situation i

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

n the whole country and on a psychological atmosphere in the society at large and within the family in particular. Traditionally, antiabortion beliefs are very strong even in the most demo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

cratic societies but on certain conditions even conservatives agree that abortion may be necessary or even inevitable. Personally, I believe that the society must be very careful resolving

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the problem weather to support or completely reject antiabortion ideas but, anyway, I am convinced that women must have a choice and a chance for abortion.

In my work I’m going to explai

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

n my viewpoint and certainly, I’ll try to analyze the degree antiabortion concerns individual and other constituent parts of our society. First of all, I would like to refer to some statis

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tic data which prove that we can’t forbid abortion, particularly in well-developed countries. According to Henshaw and Van Vort, only in the USA, among 6.2 million pregnancies that occur e

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ach year, 1.6 million end in abortion, it gives an abortion ratio of 347.8 abortions per 1000 live births (1992). The data may vary depending on the country and its level of development bu

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t still the numbers are very impressive. Also we shouldn’t forget that women in despair may commit desperate acts which may have fatal results.

But I want to underline that abortion is no

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t the problem of women only it is the problem of the whole society. To prove this statement I think it will be enough to mention that over 1000 violent attacks on abortion clinics and doct

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ors were committed from 1977 to 1991 and we should remember that a lot of attacks remained unreported (Grimes, 1991). So, it means that definite social groups are ready to defend their ant

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

iabortion belief even by the violation of law. Another evidence of social significance of the problem is the fact that in some communities in the USA, for example, Boulder, Colorado, women

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

are legally protected from antiabortion protestors (Hern, 1991). It is also noteworthy that about 12 % of Americans are totally against abortion while others who are either pro or contra

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

abortion can change their mind under certain circumstances such as the danger to woman’s life, the pregnancy as the result of rape, etc.

However, antiabortion belief may also cause proble

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ms within families which are part of the society. The fact is that it is extremely important for a woman to have a supportive atmosphere from the part of the closest relatives, namely husb

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

and and parents. Specialists highly recommend taking the abortion decision by both partners that may make the family stronger while disagreement can lead to divorce. But we also should rem

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ember that women cannot be forced to abortion as well. So the role of the family in taking the decision is not less important than the influence of the community or personal beliefs.

Taki

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ng into account all above mentioned, I want to say that antiabortion is a social phenomena that concerns not only a woman but also her family and the society she lives in but we should rea

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

lize that women have to have a chance for abortion and make a conscious choice for or against it because it is their moral and legal right. Moreover, it is evident that even violation of l

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

aw aiming at a total forbidden of abortion is doomed to fail because the only result that the forbidden may have is the increasing of illegal abortions and greater risk for women’s health.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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