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Billions have been spent in aid going into Africa. We have tried to teach Africans to farm, use condo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ms, prevent HIV-AIDS and it seems to be no use. The Africans have been killing off the Great Apes cau

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

sing massive extinction, causing wars and the more we give the more they take. It is time to stop thi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s insanity. Each time we bring more food they demand more and have more babies and more mouths to fee

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

d.

They refuse to listen to warnings about HIV-AIDS and the corruption is ramped, much of the money

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and food we send does not get where it is suppose to go and it is often hijacked and then held for ra

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nsom or used to feed guerilla armies who remain strong as they go and kill the weak. HIV-AIDS is comp

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

letely out of control now and we cannot allow this to spread.

Unfortunately, there is only one human

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e thing left to do, quarantine the entire continent and allow them to fend for themselves and cut off

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

all aid monies. Many will disagree with this notion and think that such a solution is a pitiful excu

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e for someone who cares about humanity. Yet in reality it is the best thing to do for "all" humanity.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

If Africa wants to fix itself it will, if not it will not. Anything we do only makes things worse.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

It is time to caste emotion aside and stop pretending that the solutions are simply more of the same

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on a larger scale, these are not the solutions, they never were. This is merely human empathy getting

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

in the way of reality. Stop sending money, stop sending food, stop playing games and stop pretending

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

you are making a difference. The problems are worse, because we are helping. We are making them weak

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

and un-responsible; we are giving fishes, instead of teaching.

We have tried to teach them to farm,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

use condoms, upgrade their civilization; they are not interested in learning. We need to stop this i

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nsanity and look to our own civilization and society and fix things here first, we need to be strong

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

or we are no good to anyone. You cannot help someone against their will, I thought everyone knew that

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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