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Asian Elephants

Asian elephants are sometimes known as Indian elephants. They are one of the three living species of elephant. Asian elephants are f

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ound mostly in India, Indochina, Indonesia, and Sri Lanka. Asian elephants are smaller than African elephants and Asian elephants also have smaller ears. This

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is one of the best ways to tell Asian elephants apart from African elephants. The height of an Asian elephant ranges from 7-12 feet and they weigh approximate

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ly 3.25 to 5.5 tons. There are other physical characteristics that separate Asian elephants from their African counterparts. They have a more arched back and

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

also have more nails on the feet. While both male and female African elephants have tusks, female Asian elephants usually do not have these tusks. Females tha

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

t do have tusks often have tusks that are small and hard to see.

Behavior of Asian Elephants

Elephants travel in migratory routes that are seasonal i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n nature. These routes often take the Asian elephants through wet and dry zones. The oldest member of the herd is the elephant charged with remembering where

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the routes lead. Asian elephants live for about 60 years when they are in the wild and 80 years when they are in zoos and other captive environments. The fema

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

les live in small groups that are led by the oldest female in the group. The herd that elephants travel in consists of relative elephants. Male elephants are

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

called bull elephants. They like to travel alone and often become involved in conflicts over female elephants during the mating season.

Domestic Use of Asian

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Elephants

Asian elephants have been domesticated for many purposes. In Southern and Southeast Asia, elephants have been used for forestry purposes becaus

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e their tusks and large size make it easy for them to knock down small trees and brush. Asian elephants have also been used during ceremonies for many centurie

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s. Some areas charge money to tourists to see Asian elephants in the wild, but it is difficult to do this because elephants may damage property.

Danger of

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Asian Elephants

Because of their size, Asian elephants are rather dangerous. They have tusks and large bodies that can be used to destroy property and c

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ause harm to humans and other animals. Adult males are particularly aggressive because of the surge in testosterone they experience after they go through puber

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ty. This aggression gives them the ability to cause a lot of damage in a short amount of time.

Subspecies of Asian Elephants

There are four subspeci

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

es of Asian elephants. The Indian elephant (E. m. indicus) lives in southern India, northwest India, and the foothills of the Himalayans. This subspecies has

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

males that usually have tusks. The Sri Lankan elephant (E. m. maximus) only lives in Sri Lanka. Most of the elephants do not have tusks whether they are male

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

or female. The Sumatran elephant (E. m. sumatrensis) lives in Sumatra. This elephant is sometimes known as the pocket elephant because of its small size. The

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

Borneo elephant (E. m. borneensis) is the smallest subspecies and lives in north Borneo. Even though this is the smallest subspecies, it has the biggest ears.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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