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Cambodia’s current employment issue is one of the most heated political socialization, sinc

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e it is the matter of everyone’s daily needs. Because of such the drawback, almost everyone

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s concern is “employment.” Let’s me just define the term employment from my personal perspe

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ctives. Employment does not only mean that one is hired with pay by individual or legal ent

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ty, but it must have more criteria. The pay made by the employer must meet the daily need o

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

those employed; moreover, respect from employer and dignity of the employed must also be g

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

uaranteed.

One of the things that have shocked me is that there are countries in South-Eas

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Asia and other parts of the world, are advertising for home servants, construction workers

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and other blue-collar workers from Cambodia. I do not oppose to the ideas of seeking emplo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ments and I do not discriminate manual workers, but at least I don’t want to see those adve

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tisements on the periodicals; this I think, reveals our low-esteem. Such the advertisements

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

, for me, have turned other people around the world to see underestimated image of Cambodia

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

and her people.

Cambodia is now viewed differently from the past, not like what I have quo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ted from HENRI MOUHOT:

“If you interrogate the Cambodians as to the founders of Ongcor-Wat

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

you invariably received one of these four replies: “It is the work of the Pra-Eun, the kin

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

of angle;” “It is the work of the giants;” “It was built by the leprous king;” or else, “I

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

t made itself.” (p. 279).

For the purpose of this scope of article, I don’t mean to show t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e ways to better our images, but I want you the readers and our government to think about m

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

y expression and strive for approaches to better our current images to the world. I know th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s is a really hard vocation, and so willingness and cooperation is the must for the trigger

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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