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VoIP or Voice Over Internet Protocol is an emerging technology that with the right equipment and a provider, enables voice communications or the audio content of a phone conversation to be tran

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

smitted in digital form over the internet. The advantage of this is that a standard telephone line is not required for VoIP.

As VoIP is an ever evolving technology, it is important to familia

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rize oneself in latest developments prior to making a commitment to a particular phone, provider or setup.

But let’s look at some of the basics and how practically anyone can give this technol

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ogy a ‘run’ without dipping deep into the pockets.

The Basics
VoIP has a range of options and abilities depending on the service and equipment utilized. These include:
• Only

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

calling other people using the same service;
• Ability to call any phone number including long distance, international, mobiles and of course local;
• Calling directly from a compute

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

r using a microphone or VoIP telephone; and
• Calling from an ordinary phone which is plugged into an Analog Telephone Adaptor or ATA.

Equipment Required
Given that this is Vo

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ice over Internet, it stands to reason that an internet connection is necessary – albeit one of high speed (broadband).

Depending on the service being utilized it may be as simple as a microph

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

one, or a VoIP telephone, or an adaptor that a normal phone can plug into with the adaptor plugging into an Ethernet connection.

So How Can I Make Calls for Free?
There is a range

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

of free VOIP software on the internet. A well know one is Skype at www.skype.com where users can make calls to landlines and mobiles for a fee but call each other for free.

Ok so you see the

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

limitation here. To get free calls the person you wish to contact also needs to be a user of the same service. Whilst this is true, there are ways of obtaining very low cost calls through a n

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

umber of providers. This said, the free services like Skype are well worthwhile for someone who wishes to experiment at no cost.

Service Providers
Vonage is a major VoIP provider

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and AT&T are also offering services. There are many others some of which I have listed below with no particular bias:
• 1TouchTone
• AOL Internet Phone Service
• Axvoice
•

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

BroadVoice
• Dialpad
• GalaxyVoice
• Net2Phone

For Australia several websites of VoIP providers are listed below:
• www.engin.com.au
• www.broadip.com.au
• www.fa

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ktortel.com.au

VoiPStunt – Free International Calls to a Range of Countries At the time of writing, VoiPStunt were providing free software which allows free calls between peers. Howev

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

er they are also providing free international calls to a list of international countries listed below:

Andorra, Argentina, Australia, Austria, Belgium, Bulgaria, Canada, Chile, China, Colombia

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

, Cyprus, Denmark, Finland, France, Georgia, Germany, Gibraltar, Hong Kong, Hungary, Iceland, Ireland, Italy, Japan, Latvia, Liechtenstein, Luxembourg, Malaysia, Monaco, Mongolia, Netherlands,

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

New Zealand, Norway, Panama, Peru, Portugal, Singapore, Slovenia, South Korea, Spain, Sweden, Taiwan, Thailand, Turkey, United Kingdom, United States, Venezuela.

Now that’s not a bad list. Th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e catch, a minor one, is that international calls for trial users are limited to one minute. To obtain up to 20 hours of free international calls you will need to top up your account however V

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

oiPStunt state on their website they will not touch these credits so long as you are calling the free destinations. (source – www.voipstunt.com).

Current terms and conditions should be examine

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d prior to engaging any service.

Summary
VoIP is an emerging technology with much more to come in the future. Why not enjoy free international and peer phone calls in the meantime

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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