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When searching for cell phones on eBay or the internet at large, you may have run across the term unlocked ce

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

llular phone. What does that mean? If a cell phone is locked, that means that it can only be used with one ce

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

l phone carrier company. For example if the cell phone was locked by AT&T, it can only be used with AT&T and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ot T Mobile or another carrier.

Wireless carriers started requesting that the manufacturers lock their cell

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hones a few years ago. This all came about when cellular service carriers started offering free or deeply dis

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ounted cell phones if you signed up for a one or two year contract. The wireless carriers still do this now.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

To keep someone from signing up, getting the free phone and then switching to a different carrier, the wirele

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s carrier companies had their phones locked by the manufacturer. This lock is also called a sub lock, spc loc

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

or sim lock.

How can you tell if you have an unlocked cellular phone? First you must determine if your cell

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

phone is GSM or CDMA. If your cell phone uses a sim card then it is GSM. U.S. GSM carriers are Cingular and T

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Mobile, for example. CDMA carriers are Verizon Wireless, US Cellular, Alltel, Qwest and Sprint PCS. Both type

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s of cell phone can be locked and unlocked, but only the GSM phones can be easily switched from carrier to ca

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rier.

The GSM cell phone is the easiest to deal with as once it’s unlocked, the unlocked cellular phone will

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

work with any active sim card. This means that you could insert an active T Mobile or Cingular sim card into

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

he phone and it will work and make a call. You may not be able to browse the web on that phone though if the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

hone is not programmed to that carrier.

CDMA cell phones do not use sim cards and therefore must be programm

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ed to work with another carrier. If you do not have the special software to do this, then it’s not possible t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

unlock the phone. CDMA phones are pretty much locked to the carrier they were made for.

If you want an unlo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ked cellular phone, you can buy on one on eBay already unlocked. Or you can find a company on eBay or the int

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rnet that does business unlocking cell phones. Some of these companies can unlock the cell phone remotely too

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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