Just Answers - Communications

When a business needs a bandwidth connection for their voice/data network applications they almost always choose a T1 or T3 connection. What is a T1 and a T3 con

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nection? Why are there better than dsl and cable for business needs?

T1 (1.544 Mbps) and T3 (45 Mbps) connections are traditional business-class digital leased p

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

one lines. The technology is pre-cable and pre-DSL. The main advantage is service: If either one goes down, the phone company will bend over backwards to resolve

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

he issue as soon as possible. Business rely on these lines for their income and a downed line can cost thousands of dollars an hour. They also have time-tested mo

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

itoring and diagnostic capabilities to keep them up, so they are more reliable.

A T1 breaks down into 24 channels. Each channel can either be used for a phone li

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e or 64 Kbps of Internet. A business can have 8 phone lines and 1024 Kbps of Internet (16 X 64 Kbps) over a T1 for on average between $300-$500. This is less expe

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

sive than paying for 8 phone lines + DSL/cable Internet making it better for them.

A T3 breaks into 672 channels and costs several thousand dollars a month. Howe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

er, T3 (or DS3) prices have been dropping steadily the last few years and can usually be found for between $3-4,000 in most areas. however, this still makes the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ost impractical for smaller businesses in many cases.

Often a business will optimize capability and cost by choosing to install a fractional T1 or T3 rather thsn

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

full. The obvious benefit is reduced cost....and scalability can be built in for those times when surge capability is needed or strategic business growth is plan

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ed.

They are also different in that they don't connect directly to the Internet; they connect from one customer to another. So, for example, you could have a pri

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ate line between two businesses with no Internet security hazards. Many people of course simply connect them to an ISP (whom you then have to pay an additional fe

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

on top of what you pay Ma Bell for the T1 line).

They are symmetrical, unlike most DSL and cable lines; you get the same speed in both directions. Also importan

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

for businesses, especially those exchanging data between offices.

Like DSL lines, and unlike cable lines (which are shared), they are dedicated to one customer.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Cable service is often unavailable to businesses, so that's another difference.

Not surprisingly, both can be expensive for a small business, T3's absurdly so. C

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

st mostly depends on distance. This boils down to two simple components; local loop (the cost the local incumbent charges to transport the signal from the end us

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r's central office, otherwise known as a CO, to the point of presence, otherwise known as a POP, of the carrier) and the port (the cost to access the telephone ne

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

work or the Internet through the carrier's network). Typically, the port price is based upon access speed and yearly commitment level while the loop is based on g

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ography. The further the CO and POP, the more the loop cost.

Unless you are running a business that cannot afford to go down for half a day, you are better off w

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

th cable or DSL service. Otherwise....for reliability, scalability, performance, and capacity you'd best evaluate your options for T1 or T3 bandwidth application

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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