Just Answers - Computers and Technology

The primary factor that determines uptime for servers in a colocation facility is power. Power outages will knock a network offline and even damage hardware such as motherboards, memory, and har

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

d drives. Despite how intrinsic power is to keeping businesses connected to their networks, only 2% to 3% of colocation facilities have the right power systems in place. The other 97% of facilit

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ies most commonly lack redundancy, multiple units carry the energy load even if one unit fails, or have units that are running above capacity, so a unit failure will cause the othe

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r units to overload and fail. Every part of the power system – uninterruptible power supplies (UPS), transfer switches or circuit breakers, generators, and power distribution units (PDU) – shoul

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

d be redundant and running below capacity.

Problem 1: Non-redundant Power Grids
Multiple PDUs connected to separate power grids and multiple UPSs should be designed into the colocat

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ion facility to offset a power grid failure. Colocation facilities with redundant power grids can connect customer servers to different grids at the same time, so that even if one goes offline,

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the other will work, keeping the network running without interruption.

Problem 2: Non-redundant UPSs
The UPSs supply power during an outage until the generator can come online; if t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e UPSs do not turn on immediately at the time of failure, then the network will go down. Even with high quality UPSs, failures are common, so it is critical for there to be multiple redundant UP

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

S units in an “n+1” configuration – all of the necessary UPSs, plus an extra. Functionally, this means that each UPS runs sufficiently below capacity to handle a unit failure without the other u

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nits overloading. If there are two UPSs, then each unit must run below 50%, so that if one fails, the other can continue without overloading. If there are three units, each must run below 66%; f

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

our units, below 75%. The current load is shown on the display on the front of the UPS.

Problem 3: Transfer Switch Failures
Most colocation facilities use mechanical transfer switc

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

hes, which are not as dependable as circuit breakers, to switch power from the electric utility to the generator. These switches are one of the most common places the power system fails. Without

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

redundant switches to transfer power at the same point, a transfer switch failure will mean that a network goes down.

Problem 4: Insufficient Generator Capacity
Generators supply p

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ower during an outage. To run without overloading, the generator must have capacity to run 1.5 times the total building load. Ideally, a colocation facility should have a redundant backup genera

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

or in case the primary generator fails, and the facility should have a process in place for switching power between generators. Having multiple generators is not the same as having redundant gen

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

erators. One of the most common generator problems with colocation facilities is that the facility started out with a small generator and added generators as it grew. This creates multiple point

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s where power has to be transferred during an outage, increasing the likelihood that a network will go down. As a practical consideration, the generators must be well-maintained, tested monthly,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

and fully supplied with fuel.

Points to Consider
Fewer than one in twenty colocation facilities have the best power systems in place despite the fact that power systems have the mo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

st impact on network uptime. Without well-maintained and redundant components running below capacity at every part of the system, network performance as well as server performance and equipment

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

lifetime will suffer. To make sure that the power system at a colocation facility is robust enough to handle power and equipment failures, two words should be remembered: capacity and redundancy

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.justanswers.org.ua/article/174722/justanswers-Four-Power-System-Problems-Common-in-Colocation-Facilities.html">Four Power System Problems Common in Colocation Facilities</a>

BB link (for phorums):
[url=http://www.justanswers.org.ua/article/174722/justanswers-Four-Power-System-Problems-Common-in-Colocation-Facilities.html]Four Power System Problems Common in Colocation Facilities[/url]

Ozana Giusca is someone who knows how to spot an opportunity. With the rapid development of Eastern Europe, she had a sense that there was a lack of quality resources available to companies in both Bulgaria and Romania to establish successful business ventures. In addition to this, she also found that Western companies needed quality advice when trying to business in the Eastern European Market. Put the two ideas together and Bridge Europe Consulting was born...

The birth of eBay has helped many organizations raise money with eBay fund raising campaigns. There are some distinct advantages, and some definite disadvantages to...

Without question the most critical skills in sales management are recruiting, selecting and hiring the best sales representatives. Yet why do so many sales managers come up short in these vital skills? If your goal is to land a top sales performer, then you might want to compare how flying a plane is like picking a superb sales person.

Tags

Links

Just Answers - Four Power System Problems Common in Colocation Facilities

Related Articles: