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I've read some non-Cisco documentation that EIGRP will not allow adjacencies to form when secondary addresses are used.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

This is incorrect, but there is one common error that can result if both addresses are not secondary. Let's take a l

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ok at R2 and R3, which will be using secondary addresses to form an EIGRP adjacency.

R2(config)#interface ethernet0

R

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

(config-if)#ip address 172.12.23.2 255.255.255.0

R2(config-if)#ip address 23.23.23.2 255.255.255.0 secondary

R2(confi

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

)#router eigrp 100

R2(config-router)#no auto-summary

R2(config-router)#network 23.23.23.0 0.0.0.255

R3(config)#inter

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ace ethernet0

R3(config-if)#ip address 172.12.23.3 255.255.255.0

R3(config-if)#ip address 23.23.23.3 255.255.255.0 se

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ondary

R3(config)#router eigrp 100

R3(config-router)#no auto-summary

R3(config-router)#network 23.23.23.0 0.0.0.255

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Here's the partial output of show ip eigrp neighbor on R3:

R3#show ip eigrp neighbor

IP-EIGRP neighbors for process 1

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

0

H Address Interface

0 172.12.23.2 Et0

The adjacency has formed! Note the address

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s actually the primary IP address on the interface, even though we used the secondary network number in the EIGRP netwo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

k command. Personally, I stay away from secondary network numbers if at all possible, but you should know that seconda

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y IP addresses can be used to create EIGRP adjacencies.

What's the common error with using secondary addresses, you as

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ed? It's when an address from the same subnet is the primary interface address on one neighbor and the secondary inter

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ace address on another. Let's say we had configured R2 and R3 as follows:

R2(config)#int e0

R2(config-if)#ip address

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

3.23.23.2 255.255.255.0

R3(config)#interface ethernet0

R3(config-if)#ip address 172.12.23.3 255.255.255.0

R3(config-

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

f)#ip address 23.23.23.3 255.255.255.0 secondary

On R2, we get this message:

01:54:05: IP-EIGRP: Neighbor 172.12.23.3

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

not on common subnet for Ethernet0 (23.23.23.2 255.255.255.0)

Since we configured 23.23.23.2 as a primary interface ad

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ress on R2, the EIGRP process is looking at the primary interface address on potential neighbors. Since R3's primary e

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

hernet0 address is 172.12.23.2, you get the "not on common subnet" error message - and what you don't get is an adjacen

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

y! That's something to be aware of on your 642-901 BSCI exam as well as when working with EIGRP in production networks

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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