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What they didn’t tell you at Harvard Screenwriting School is that the Hero's Journey is the template upon which the vast majority of successful stories and Hollywood blockbusters are based upon – un

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

derstanding this template is a priority for story or screenwriters.

Most people familiar with this story structure perceive it as the “Quest Theory.” That is, they can see how it can be a template

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

for stories such as Star Wars, Lord of the Rings, Jason and the Argonauts and so forth, but they resist the idea that it explains or is the core behind other stories such as Million Dollar Baby (Aca

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

emy Award Winner Best Film 2004).

In fact, if you deconstruct the Academy Award Winners (Best Films) of the last few decades, you quickly realise that they are all based around the Hero’s Journey t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

emplate. That there is, in fact, only one story.

The following is a basic deconstruction of Million Dollar Baby (Academy Award Winner Best Film 2004):

Call to Adventure – where the hero is

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ushed to resolve a challenge. Maggie needs to escape her White Trash roots and Frankie needs to resolve issues concerning his daughter.

Refusal of the Call – where there is refusal, resistance, war

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ning and foreboding. Frankie refuses to train Maggie.

The Supernatural Aid – where a mentor encourages the hero along the path. Eddie (Morgan Freeman) begins to help Maggie with her training and si

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ultaneously guides Frankie towards her. As is usual, the supernatural aid has a challenge of his own (Danger Barch).

First Threshold – where a point of no return is crossed. Maggie persists in the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

gym. There is no dissuading her or going back for her.

Physical Separation (Belly of the Whale) – where the hero physically separates from his Old World and heads into the Transformation. Willie le

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ves Frankie, who has little else to do but train Maggie.

Transformation (Road of Trials) – where the hero significantly, but not completely, transforms. Maggie becomes a professional boxer.

The Id

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

eal and the Seizing of the Sword – where the hero faces a difficult choice and journey to (often) the heart of the antagonism. Maggie buys her family a house and Frank takes on the role of father.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Rebirth Through Death – where the Hero is reborn. Eddie saves Danger Barch from the gym bully; Maggie doesn't know what to do about the bear.

Atonement with the Father – where the hero confronts th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

obstacle to the apotheosis. Maggie loses to the blue Bear.

Apotheosis – where the hero has the illumination. Maggie should have listened to Frank and protected herself.

Ultimate Boon – both hero

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

and heroine get a family.

Refusal of the Return – where the hero is repulsed by his Old Self or, on a practical level, there is refusal on some level. Frankie refuses to go back to the gym.

Magic

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

light – where the hero attempts to escape from the antagonism or, for some reason, is unable to confront it. Frankie takes Maggie away and attempts to find doctors who can reverse the situation.

Re

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

scue for Without – where the hero is pulled back toward his or her challenges. Maggie's family return; Frankie wants to replace them and resists their arrival.

Crossing the Return Threshold – where

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

the hero confronts the antagonism. Maggie loses her legs and asks Frankie to kill her.

Master of the Two Worlds – where the antagonism is defeated. Frankie kills Maggie.

Freedom to Live – where th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e hero is freed from the antagonism. Frankie does not return to the gym.

The detailed, complete deconstruction and the Complete 188 stage Hero’s Journey and FREE 17 stage sample and other st

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ry structure templates can be found at http://managing-creativity.com/

You can also receive a regular, free newsletter by entering your e

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mail address at this site.

Kal Bishop, MBA

**********************************

You are free to reproduce this article as long as no changes are made and the author's name and site URL are retained

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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