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The Hero's Journey (Monomyth) is the template upon which the vast majority of succes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

sful stories and Hollywood blockbusters are based upon. In fact, ALL of the hundreds

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

of Hollywood movies we have deconstructed (see URL below) are based on this 188+ sta

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e template.

Understanding this template is a priority for story or screenwriters. T

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

is is the template you must master if you are to succeed in the craft.

THERE IS ONL

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ONE STORY

THE HERO'S JOURNEY:

a) Attempts to tap into unconscious expectations th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

audience has regarding what a story is and how it should be told.

b) Gives the wri

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ter more structural elements than simply three or four acts, plot points, mid point

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

nd so on.

c) Gives you a tangible process for building and releasing dissonance (es

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ablishing and achieving catharses, of which there are usually four).

d) Gives you a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

universal structural template upon which you can superimpose your situational story.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and more...

ABRIDGED TIP(S):

*****Romantic Challenge*****

The Romantic Challenge

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

is developed or further made explicit (post Trial 3 and the conquest of the Outer Ch

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

llenge). The Hero has come a long way but he (as well as the audience) are reminded

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

that this has yet to be conquered: In An Officer and a Gentleman (1982), Zach resist

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Paula when she says she's going after what she wants (him). In Dances with Wolves (

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

990), Stands with a Fist is increasingly attracted to John.

*****Leaving the First

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

hreshold*****

Upon leaving the First Threshold, a New Self is slowly becoming appar

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nt. The Hero leaves behind the Old Self. Often this is expressed by a Change of Clot

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

es. In Bonnie and Clyde (1967), Bonnie puts on New Clothes and is dressed nicely now

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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