Just Answers - Finance

When applying for a home loan (mortgage), there are multiple qualifying facto

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rs considered such as the debt to income ratio (DTI). In other words, the rat

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

o of what comes in and what goes out. What comes in are your incomes and - or

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

revenues. What goes out are all your revolving accounts, mortgages, car loans

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

etc on you credit report.

Basically the calculation is done this way:

M

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nthly income before taxes: $4250
Credit card minimum payment: $850

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ar loan: $375
The new mortgage payment: $1550
Taxes and Insurance:

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

175
Total out: $2950

Expenses / incomes = $2950/$4250= 0.69

I

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

this case, your expenses are too high and your income is too low.... This is

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

not GOOD! Some banks (mostly subprime banks) will let you go up to 55% or so.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Most Prime banks will like it a lot lower than that. Even if you have great

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

FICO score, the DTI might bring you from a Prime Bank to a Sub-prime Bank jus

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

because your DTI is too high. Once again, ask questions to your loan office

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

. If they put you into a sub-prime bank, they might charge you more points.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

What you need to do in this case (and TELL your loan officer about this) if y

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

u refinance, you get some extra cash out, you pay a few credit cards and auto

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

atically it brings your ratio down. But you need to have equity in the house

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

o do it or you will not be able to refinance using the regular channels. Ther

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

are other options but they are costly!

If we wanted to be more complicated

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

here are the front and the back but we don't need to go there for now.

Enjoy

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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For as long as employment has been the mandatory way in which to make money, people have been looking for easy escapes. The dream of earning a huge salary without much work, has been the goal of many but has been realised by very few.

Everybody who is or has been in debt has considered debt consolidation loans as an option. However, few can get approved for secured consolidation loans because not everybody has enough equity left on their homes. And though unsecured consolidation loans exist, they are not easy to get. And often, this question rises: Will I be able to get an Unsecured Consolidation Loan?

If you have more than one form of debt, especially credit card debt, then this strategy is critical for you. Learn how you can actually decrease your debt faster and increase your credit score at the same time!

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